GLP-1 receptor agonists like semaglutide and tirzepatide are transforming the fields of regenerative medicine, longevity, and performance health—but they’re not just for weight loss. In this episode of the Rare Wellness Podcast, Dr. Jamie Lewis breaks down how these powerful peptides work, their surprising benefits beyond metabolic health, and their role in reducing inflammation, enhancing cognitive function, supporting pain management, and even improving recovery and healing.

🔹 How GLP-1 RAs work to regulate blood sugar & metabolism

🔹 The unexpected benefits for cognitive health & neuroprotection

🔹 How these medications help with pain relief & inflammation

🔹 Why GLP-1s are a game changer for longevity & vitality

If you're curious about these cutting-edge treatments and how they can optimize your health, this episode is for you!

💡 Learn more about Dr. Jamie Lewis & book a consultation at: www.nwc4rm.com and www.rarewellness.com

👍 If you found this episode valuable, please like, subscribe, and share to support our mission of making wellness accessible to all.

Works Cited:

Wilding, J. P., et al. (2021). "Once-Weekly Semaglutide in Adults with Overweight or Obesity." The New England Journal of Medicine.

Jastreboff, A. M., et al. (2022). "Tirzepatide Once Weekly for the Treatment of Obesity." The New England Journal of Medicine.

Davies, M., et al. (2022). "Semaglutide 2.4 mg in Adults with Obesity or Overweight: Effects on Weight Loss and Maintenance." The Lancet.

Wadden, T. A., et al. (2022). "Weight Regain After Discontinuation of GLP-1 Receptor Agonists." Obesity Reviews.

Drucker, D. J. (2018). "Mechanisms of Action and Therapeutic Applications of GLP-1 Agonists in Inflammation and Neuroprotection." Cell Metabolism.

Holst, J. J., et al. (2020). "GLP-1 and its Role in Modulating Immune Function and Inflammation." Diabetes Care.

Ashina, M., et al. (2021). "GLP-1 Agonists in the Modulation of Pain Hypersensitivity: Implications for Migraine Management." The Journal of Headache and Pain.

Healthline. (2022). "Ozempic for Severe Osteoarthritis Knee Pain." Retrieved from healthline.com.

"Glucagon-like peptide-1: a multi-faceted anti-inflammatory agent." Frontiers in Immunology, 2023. Retrieved from frontiersin.org.

"Beyond Glycemic Control: Exploring GLP-1 Agonists for Diabetic Foot Ulcer Healing." Diabetic Foot Online, 2024. Retrieved from diabeticfootonline.com.

"GLP-1 drugs linked to fewer post-surgical complications in diabetic patients." News-Medical, 2025. Retrieved from news-medical.net