A reversible liver condition is the fastest growing cause of liver transplantation in Western countries: Metabolic dysfunction-associated steatotic liver disease—or MASLD—affects patients worldwide. It’s characterized by excessive fat accumulation in the liver and can progress into more severe forms of liver disease, potentially resulting in fibrosis, cirrhosis and liver failure.

Risk factors for developing liver disease include obesity, insulin resistance, type 2 diabetes, and metabolic syndrome. Genetics, unhealthy dietary habits, and a sedentary lifestyle can also play significant roles in its development. Diagnosis typically involves imaging examinations along with blood tests that assess liver function and rule out other causes of liver disease.

Disease management focuses on lifestyle modifications such as diet and exercise, though new medications are now being prescribed to slow and potentially reverse this condition. Regular monitoring of disease progression is also crucial for successful treatment.

In this episode, experts in the field of liver disease address the progress happening in the recognition, diagnosis and treatment of the disease.

Host Matt Gee, Director of Collaborations and External Engagement at Siemens Healthineers, is joined by Dr. Michelle Long, International Medical Vice President of Metabolic Dysfunction-Associated Steatohepatitis at Novo Nordisk and Director of Clinical Research for the Section of Gastroenterology and Hepatology at Boston University; Dr. Arun Sanyal, Professor of Medicine, Physiology, and Molecular Pathology in the Division of Gastroenterology at Virginia Commonwealth University; and Michael Betel, President and Founder of the Fatty Liver Alliance.

What you’ll learn in this episode:

• One of the biggest obstacles to diagnosing MASLD before it progresses stems from the lack of visibility and awareness of the disease
• MASLD is a reversible disease when caught in time
• MASLD is more complex than a patient’s diet or lifestyle—metabolic dysfunction plays a role
• Non-invasive testing has become an important tool in advancing patient care

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Radiotherapy plays a vital role in cancer treatment. In Europe alone, incidents of cancer are projected to rise around 20% by 2040, mainly due to an increasingly aging population. It’s numbers like these that emphasize the importance of pushing boundaries in radiotherapy.

With AI-optimized workflows, it’s possible to speed up treatment planning and ensure highly personalized therapies and technology like auto contouring can protect healthy organs during irradiation by means of AI. This implementation, however, is often met with challenges like staff shortages and inconsistencies with data collection, highlighting the need for more efficient implementation strategies.

In this episode, experts in the fields of radiotherapy and cancer treatment address the amazing headway being made in the world of radiotherapy as well as some of the key roles that current technology can play in the future.

Host Sasa Mutic, President of Radiation Oncology Solutions at the Varian Business Area of Siemens Healthineers, is joined by Valery Lemmens, a member of the Board of Directors at Maastro Radiotherapy Clinic in the Netherlands and creator of the Dutch Cancer Atlas; as well as Joost Verhoeff, radiation oncologist and professor of radiotherapy at Amsterdam University Medical Center; and Indrin Chetty, Vice Chair and Director of the Division of Medical Physics at Cedars-Sinai in Los Angeles.

What you’ll learn in this episode:

• By using a digital twin, medical professionals can review existing health records and continually compare that information with patient data
• With adaptive radiotherapy, radiation dosages can be tailored to circumstances like tumor size, type, and position and proximity to vital organs
• The Dutch Cancer Atlas interprets and publishes data in a context that increases awareness of regional differences in cancer incidents
• The unique role that data plays in the advancement of cancer care
• The deep troves of data that already exist within radiotherapy departments can play a key role in the integration of AI into cancer treatments
• Widespread availability of data creates the opportunity for automated treatment planning and outcome prediction

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Indrin Chetty

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With significant disparities in diagnosis, treatment, and funding when compared to men, women’s health has long been underserved. These gaps affect not only individual health outcomes, they also have societal and economic implications which are highlighted by a recent report by the World Economic Forum and The McKinsey Health Institute which addresses a $1 trillion dollar opportunity to improve lives and economies by mitigating these disparities.

Factors like societal perception, clinical practice, and financial investment all play an important part in women’s health. Addressing the gender health gap and overcoming issues like the misdiagnosis of diseases in women, increasing women’s representation in clinical trials, and advocating for greater financial investment in women’s health are all crucial steps in building a more equal healthcare system for all.

Today, we’re joined by board members of the World Economic Forum’s Global Alliance for Women’s Health to discuss how building a more equitable healthcare system can drive meaningful change, improve healthcare for women, and create access to significant economic potential worldwide.

In this episode, host Elisabeth Staudinger, Member of the Managing Board of Siemens Healthineers, is joined by fellow World Economic Forum’s Global Alliance for Women’s Health board members Nadia Fettah, Minister of Economy and Finance for the Government of Morocco and Shyam Bishen, Head of the Centre for Health & Healthcare at the World Economic Forum.

What you’ll learn in this episode:

• Despite living longer, women spend 25% more time in poor health than men
• Women are twice as likely to be misdiagnosed after having a heart attack than men. Along with misdiagnosis and premature discharge, female cardiac patients are also less likely to be prescribed secondary prevention measures after experiencing a cardiac event
• How the Global Alliance for Women's Health is pooling together efforts in research, regulation and funding to close the gender healthcare gap
• Success stories that give hope on the path to healthcare equality

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