Matt Spiegel opened his show by breaking down the Cubs' 14-2 win against the Marlins on Saturday and by discussing how important young center fielder Pete Crow-Armstrong has been to the bottom of the lineup. Later, Spiegel discussed the White Sox's 13-4 loss to the Tigers on Saturday. He also had his son Rubin do the math to see how many wins the White Sox need to earn to avoid breaking the record for the most losses by an MLB team in a single season.

In the second hour, Matt Spiegel was joined by Ryan McGuffey of NBC Sports Chicago to discuss the White Sox's woeful season and how they can improve the state of their organization moving forward.

In the final hour, Matt Spiegel was joined by Sahadev Sharma of The Athletic to discuss Cubs outfielder Seiya Suzuki's hot bat and the club's bullpen. Later, Spiegel shared a clip from his The PBP podcast in which he interviewed Astros broadcaster Todd Kalas.

In for Matt Spiegel, Gabe Ramirez opened his show by recapping the recent play of the Cubs and White Sox. Later, MLB Pipeline senior writer Jim Callis joined the show to discuss the top prospects of the Cubs and White Sox and to break down his outlet's recent update to its list of the top 100 prospects in the game.

In the final hour, Gabe Ramirez replayed Cubs icon Ryne Sandberg's heartfelt interview from Thursday during the Cubs for a Cure Radiothon, during which he announced he's cancer-free. Later, Score host Matt Spiegel joined his own show live from the broadcast booth at Wrigley Field as he prepared to work the Cubs-Blue Jays radio broadcast.