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Imagine looking across an open field and spotting something that shouldn't exist—a dire wolf, extinct for 10,000 years, running wild again. This isn't science fiction anymore. Scientists have successfully created wolf pups carrying DNA from the extinct dire wolf species, opening a Pandora's box of questions about the ethics and implications of bringing extinct species back to life.

The conversation begins with a lighthearted reminiscence about baseball and papal elections before diving into the fascinating world of de-extinction. The guys explore how Colossal, a private company dedicated to resurrecting extinct species, has combined ancient dire wolf DNA with modern gray wolf genetics to create something that hasn't existed for millennia. These massive predators once stood four feet tall at the shoulder—substantially larger than any wolf you might encounter today.

But the heart of the discussion centers on a profound question: Just because we can resurrect extinct species, should we? The team examines this from multiple angles—scientific, ethical, environmental, and even spiritual. They question whether species that went extinct through natural processes or cataclysmic events like asteroid impacts should be brought back into a world that has dramatically changed since they disappeared. Would these creatures even be able to survive in today's environment? What unintended consequences might follow their reintroduction?

This leads to broader considerations about genetic manipulation technology and its applications. While de-extinction of charismatic creatures like dire wolves and woolly mammoths captures public imagination (and investor dollars), the same technology could potentially be directed toward medical breakthroughs or preventing currently endangered species from disappearing. Is creating predators from the past the best use of these scientific capabilities?

The conversation concludes with a thought-provoking question that we will let you discover for yourselves. As we develop the power to bring species back from oblivion, this question takes on new weight and meaning.

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