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In this episode, we sit down with Bogdan Knezevic, co-founder and CEO of Kaleidoscope, to talk about a growing challenge in life sciences R&D: making smart decisions when data is scattered across teams, tools, and partners.

Bogdan explains why disconnected systems lead to costly delays, duplicate experiments, and missed opportunities. He shares how the shift from academic to industry research, where projects are shared, not siloed, requires better workflows, clearer handoffs, and more thoughtful tools.

We discuss:

• Why real-time access to decision-ready data matters more than connecting every system
• How delays between experiments quietly waste months of progress
• The hidden cost of repeating work because past data is hard to find
• Why user-friendly tools are just as important as powerful ones
• How better data management can strengthen trust with partners and investors

If your organization is working to scale R&D, improve collaboration, or simply make better use of the data you already have, this conversation is for you. Even small changes today can lead to huge gains tomorrow.

Learn more about Kaleidoscope Bio at https://www.kaleidoscope.bio/

Connect with Bogdan at https://www.linkedin.com/in/bogdanknezevic/

Ready to assess your organization’s efficiency? Connect with us at leanbydesign@sigmalabconsulting.com to uncover high-impact improvement opportunities. 🚀

Learn more about us by visiting: https://sigmalabconsulting.com/

Want our thoughts on a specific topic? Looking to sponsor this podcast to continue to generate content? Or maybe you have an idea and want to be on our show. Fill out our Interest Form and share your thoughts.

Send us a text

In this episode, we sit down with David Hirschfeld, 35-year software veteran and founder of Tekyz, to talk about why designing workflows before you start building is critical for sustainable growth.

We explore how the speed of modern tools and AI can create a dangerous illusion of progress, causing teams to skip planning and discovery. David challenges the common “build while flying” mindset and explains why taking time to think first actually speeds you up.

You’ll also hear his contrarian, but highly practical, "Launch First" approach, where sales and marketing happen before building. It’s a powerful method for validating product-market fit early, avoiding wasted development cycles, and moving fast without flying blind.

Whether you’re launching a startup, building internal platforms, or scaling R&D, this episode will reshape how you approach planning, execution, and risk.

Learn more about the Launch 1st Method at https://launch1st.tekyz.com/

Connect with David at https://www.linkedin.com/in/dhirschfeld/

Ready to assess your organization’s efficiency? Connect with us at leanbydesign@sigmalabconsulting.com to uncover high-impact improvement opportunities. 🚀

Learn more about us by visiting: https://sigmalabconsulting.com/

Want our thoughts on a specific topic? Looking to sponsor this podcast to continue to generate content? Or maybe you have an idea and want to be on our show. Fill out our Interest Form and share your thoughts.

Send us a text

Have you ever started a project only to realize you’re building something your leaders never asked for? You’re not alone.

In this episode of Lean by Design, we sit down with Marcelo Calbucci, a veteran of Amazon, Microsoft, and multiple startups, to explore the PRFAQ Framework, Amazon’s secret weapon for aligning strategy and execution.

By drafting a mock press release and FAQ before a single line of code is written, teams force themselves to clarify vision, spot roadblocks, and reach consensus across departments. The real magic comes from the collaborative review and no bullet‑filled slides, just a tight narrative that surfaces gaps in logic and focuses on solving genuine customer problems.

Whether you’re battling scope creep as a product manager or aiming for alignment as an executive, this conversation will equip you with a powerful tool to kick off your next project with crystal‑clear purpose. Tune in and learn to work backward for forward momentum.

Learn more about the PRFAQ at https://www.theprfaq.com/

Connect with Marcelo at https://www.linkedin.com/in/marcelocalbucci | https://x.com/calbucci

Ready to assess your organization’s efficiency? Connect with us at leanbydesign@sigmalabconsulting.com to uncover high-impact improvement opportunities. 🚀

Learn more about us by visiting: https://sigmalabconsulting.com/

Want our thoughts on a specific topic? Looking to sponsor this podcast to continue to generate content? Or maybe you have an idea and want to be on our show. Fill out our Interest Form and share your thoughts.