Penn and Rob wish they were invited to "We Are the World!" Magician, television presenter, and author Penn Jillette (of Penn & Teller) joins Rob Lowe to discuss his surprising favorite magic trick, the genius of Bob Dylan, 50 years of “Penn & Teller,” and his new novel.

Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Kelsey Grammer returns to "Literally” for a moving episode. The "Frasier" and "Cheers" star joins Rob Lowe to discuss his deeply cathartic new book, "Karen: A Brother Remembers," the tragic loss of his sister, his return to the world of "X-Men" and Marvel, why he still finds joy in acting, and much more.

Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

It’s always outrageous when Rob and Chelsea Handler get together! Comedian, writer, and host of the “Dear Chelsea” podcast Chelsea Handler joins Rob Lowe to discuss their perspectives on aging, the ski season, what she’s looking for in an “international boyfriend,” Rob’s early days of sobriety, and much more.

Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!