• S4:E2 - Making Sulfur Smell like Success!

  • 2025/04/21
  • 再生時間: 27 分
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S4:E2 - Making Sulfur Smell like Success!

  • サマリー

  • Join us on the Pharm to Table podcast for a delightful chat with Ethan Wappes from our South San Francisco site, as we dive into the exciting world of thiophene synthesis! Ethan is a member of our Discovery Process Chemistry group and worked alongside medicinal chemists to devise a better synthetic route towards substituted thiophenes. Ethan shares insights from his recent Org. Lett. on a novel Rh-catalyzed [3+2] method that opens the door to highly substituted dihydrothiophenes, enhancing our medicinal chemistry toolkit. We explore how this strategy not only simplifies complex thiophene syntheses but also paves the way for new drug development possibilities!

    Read the papers we discussed today:

    Fully Substituted Thiophene Synthesis via (3 + 2) with Thiadiazoles - Org Lett 2024

    Follow the Pharm to Table podcast on X - ⁠⁠⁠⁠@PharmtoTablePod

    ⁠⁠⁠⁠Visit our website at ⁠⁠⁠⁠https://podcasters.spotify.com/pod/show/pharm-to-table

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あらすじ・解説

Join us on the Pharm to Table podcast for a delightful chat with Ethan Wappes from our South San Francisco site, as we dive into the exciting world of thiophene synthesis! Ethan is a member of our Discovery Process Chemistry group and worked alongside medicinal chemists to devise a better synthetic route towards substituted thiophenes. Ethan shares insights from his recent Org. Lett. on a novel Rh-catalyzed [3+2] method that opens the door to highly substituted dihydrothiophenes, enhancing our medicinal chemistry toolkit. We explore how this strategy not only simplifies complex thiophene syntheses but also paves the way for new drug development possibilities!

Read the papers we discussed today:

Fully Substituted Thiophene Synthesis via (3 + 2) with Thiadiazoles - Org Lett 2024

Follow the Pharm to Table podcast on X - ⁠⁠⁠⁠@PharmtoTablePod

⁠⁠⁠⁠Visit our website at ⁠⁠⁠⁠https://podcasters.spotify.com/pod/show/pharm-to-table

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