This is a summary of the Huberman Lab with Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive.

They discuss the NAD pathway in human cells and its possible links to aging and health. They evaluate how supplementation can augment molecules in the NAD pathway; they compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, they discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan.

Finally, they each describe thier supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. They also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk.

Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan

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Source content: https://youtu.be/79p1X_7rAMo?si=_A6dZq9Lq-gAPJBL