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Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences.

In Exile Economics, Ben Chu lays out the dangers of the current obsession with isolationism. By focusing on some key internationally traded commodities - agriculture, energy, metals and high-technology - he demonstrates just how thoroughly enmeshed and almost unfathomably interconnected our economies have become. Exile Economics will be an essential guide to this new world in all its promise and peril.

Earth is not well. The promise of starting life anew somewhere far, far away—no climate change, no war, no Twitter—beckons, and settling the stars finally seems within our grasp. Or is it? Critically acclaimed, bestselling authors Kelly and Zach Weinersmith set out to write the essential guide to a glorious future of space settlements, but after years of research, they aren’t so sure it’s a good idea.

Stephanie Kelton's brilliant exploration of modern monetary theory (MMT) dramatically changes our understanding of how we can best deal with crucial issues ranging from poverty and inequality to creating jobs, expanding health care coverage, climate change, and building resilient infrastructure. Any ambitious proposal, however, inevitably runs into the buzz saw of how to find the money to pay for it, rooted in myths about deficits that are hobbling us as a country.

Innovation expert Ted Dintersmith took an unprecedented trip across America, visiting all 50 states in a single school year. He originally set out to raise awareness about the urgent need to reimagine education to prepare students for a world marked by innovation, but America's teachers one-upped him. He met teachers in ordinary settings doing extraordinary things. Capturing bold ideas from teachers and classrooms across America, What School Could Be provides a realistic, and profoundly optimistic, roadmap for creating cultures of innovation and real learning in all our schools.

In 2014, the world witnessed the start of a mysterious series of cyberattacks. Targeting American utility companies, NATO, and electric grids in Eastern Europe, the strikes grew ever more brazen. They culminated in the summer of 2017, when the malware known as NotPetya was unleashed, penetrating, disrupting, and paralyzing some of the world's largest businesses—from drug manufacturers to software developers to shipping companies. At the attack's epicenter in Ukraine, ATMs froze. The railway and postal systems shut down. Hospitals went dark.

"Wir, die Völker der Vereinten Nationen – fest entschlossen, künftige Geschlechter vor der Geißel des Krieges zu bewahren, die zweimal zu unseren Lebzeiten unsagbares Leid über die Menschheit gebracht hat –, haben beschlossen: Alle Mitglieder unterlassen in ihren internationalen Beziehungen jede gegen die territoriale Unversehrtheit oder die politische Unabhängigkeit eines Staates gerichtete oder sonst mit den Zielen der Vereinten Nationen unvereinbare Androhung oder Anwendung von Gewalt.

From wood to coal to oil and gas, the sources of energy on which civilization depends have always changed as technology advances. Now renewables are overtaking fossil fuels, with wind and solar energy becoming cheaper and more competitive every year. Growth in renewable energy will further accelerate as electric vehicles become less expensive than traditional automobiles. Understanding the implications of the energy transition will prepare us for the many changes ahead.

In 2023, hundreds of machine-learning scientists signed an open letter warning about our risk of extinction from smarter-than-human AI. Yet today, the race to develop superhuman AI is only accelerating, as many tech CEOs throw caution to the wind, aggressively scaling up systems they don't understand—and won’t be able to restrain. There is a good chance that they will succeed in building an artificial superintelligence on a timescale of years or decades. And no one is prepared for what will happen next.

In Jared Diamond’s follow-up to the Pulitzer-Prize winning Guns, Germs and Steel, the author explores how climate change, the population explosion, and political discord create the conditions for the collapse of civilization. Environmental damage, climate change, globalization, rapid population growth, and unwise political choices were all factors in the demise of societies around the world, but some found solutions and persisted.

Economics isn't just about numbers: It's about politics, psychology, history, and so much more. We are all economists - when we work, save for the future, invest, pay taxes, and buy our groceries. Yet many of us feel lost when the subject arises. Award-winning professor Timothy Taylor here tackles all the key questions and hot topics of both microeconomics and macroeconomics, so you can understand and discuss economics on a personal, national, and global level.

According to conventional wisdom, innovation is best left to the dynamic entrepreneurs of the private sector, and government should get out of the way. But what if all this was wrong? What if, from Silicon Valley to medical breakthroughs, the public sector has been the boldest and most valuable risk taker of all?

In this 2nd edition of Focus: Elevating the Essentials to Radically Improve Student Learning, Mike Schmoker extends and updates the case that our schools could be on the cusp of swift, unparalleled improvements. But we are stymied by a systemwide failure to simplify and prioritize; we have yet to focus our limited time and energy on the most essential, widely acknowledged, evidence-based practices that could have more impact than all other initiatives combined.

Why do well-intentioned plans for improving the human condition go tragically awry? Author James C. Scott analyzes failed cases of large-scale authoritarian plans in a variety of fields. Centrally managed social plans misfire, Scott argues, when they impose schematic visions that do violence to complex interdependencies that are not - and cannot - be fully understood. Further, the success of designs for social organization depends upon the recognition that local, practical knowledge is as important as formal, epistemic knowledge.

Political leaders, diplomats, and business executives around the world - including every president from John F. Kennedy to Donald J. Trump - have sought the counsel of Henry Kissinger, a brilliant diplomat and political scientist whose unprecedented achievements as a negotiator have been universally acknowledged. Now, Kissinger the Negotiator provides a groundbreaking analysis of Kissinger’s overall approach to making deals and his skill in resolving conflicts - expertise that holds powerful and enduring lessons.

Building on the foundation laid by Moshe Feldenkrais, Thomas Hanna's groundbreaking work completely redefines the body's potential for withstanding decline. His gentle program for the mind and body proves once and for all that so many problems we accept as inevitable over time - chronic stiffness, bad back, chronic pain, fatigue, and, at times, even high blood pressure - need never occur if we maintain conscious control of nerve and muscle, replacing Sensory-Motor Amnesia with Sensory-Motor Awareness.

An indictment of the American educational system criticizes the fact that the system has discarded the traditional goals of transmitting knowledge and fostering cognitive skills in favor of building self-esteem and promoting social harmony.

When it comes to climate change, the media, politicians, and other prominent voices have declared that "the science is settled." In reality, the long game of telephone from research to reports to the popular media is corrupted by misunderstanding and misinformation. Core questions - about the way the climate is responding to our influence, and what the impacts will be - remain largely unanswered. The climate is changing, but the why and how aren't as clear as you've probably been led to believe.

It seems like an impossible task: secure a safe future for life on Earth, at a scale and speed that the world has never seen, in the face of vast and powerful forces-not just oil tycoons and governments, but the changing climate system itself. The odds are against us, and we are running out of time. But it doesn't have to be this way. Around the world, geophysicists and mathematicians, oceanographers and meteorologists, engineers, economists, psychologists and philosophers have been using their expertise to develop a deep understanding of the crises we face.

A major new collection from "arguably the most important intellectual alive" ( The New York Times). Noam Chomsky is universally accepted as one of the preeminent public intellectuals of the modern era. Over the past thirty years, broadly diverse audiences have gathered to attend his sold-out lectures. Now, in Understanding Power, Peter Mitchell and John Schoeffel have assembled the best of Chomsky's recent talks on the past, present, and future of the politics of power.