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In this episode of The Uprising Show, host Vivek sits down with Manush Saydmohammed, Ph.D., MBA, co-founder and CEO of ZEGENEX Inc., a Pittsburgh-based startup developing innovative wound healing solutions. Manush shares his remarkable journey from humble beginnings in Kerala, India, through a career in biomedical research across India, Japan, and the US, to becoming an entrepreneur driven by the desire to translate cutting-edge science into real-world medical solutions.

The conversation dives into how the COVID-19 pandemic inspired Manush to transition from academic research to the world of startups, and explores the science behind ZEGENEX’s groundbreaking small-molecule cream designed to accelerate healing in chronic wounds like diabetic foot ulcers. Manush candidly discusses the challenges of moving novel therapies from the lab to the clinic, the importance of patents and collaboration, and the regulatory hurdles unique to new drug entities.

They also touch on the exciting future of health tech, from AI-accelerated drug discovery to gene editing and personalized medicine. Manush closes by sharing personal insights on entrepreneurship, including the importance of mindset, adaptability, and the inspiration he draws from innovators like Mark Cuban. Whether you’re passionate about science, startups, or healthcare innovation, this episode offers an inspiring look into the entrepreneurial journey and the potential to make a real impact in patient care.

Timestamps:

00:00 From Kerala to the US: Research Journey

04:24 Navigating Transitional Unlearning

07:08 Pioneering Treatment for Chronic Wounds

11:44 Product Success: Feasibility and Viability

16:04 Zebrafish: Ideal Heart Regeneration Model

19:45 Patents Ensure Product Credibility

22:43 New Drug Device Regulatory Pathway

26:46 AI in Drug Discovery

30:27 Stem Cell Industry Exploration

31:33 Diabetic Foot Ulcer Study Phases

36:50 Change Habits, Mark Cuban Inspiration

38:30 "Challenging Fundraising, Hopeful Future"

The Uprising Show Website: https://theuprisingshow.com/

Vivek Nanda's LinkedIn: https://www.linkedin.com/in/viveknanda1/

Vivek Nanda's Twitter: https://x.com/vickks

TopHealth Media Website: https://tophealth.care/

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Welcome back! In this episode, we sit down with Scott Chetham, CEO and co-founder of Faro Health, for an in-depth conversation about revolutionizing clinical trials with data-driven technology. Scott shares his unexpected journey from Australia’s Gold Coast to becoming a healthcare tech leader in San Diego, and how his upbringing, shaped by his parents’ perseverance and partnership, inspired his approach to entrepreneurship.

In this conversation, Scott digs into the complexities of clinical trial design and the inefficiencies plaguing the industry, especially the over-reliance on outdated tools like Microsoft Word. Discover how Faro Health is modernizing the way trials are designed and managed, harnessing AI and automation to reduce costs, accelerate timelines, and improve patient experiences. Scott offers candid insights into the real problems facing pharma companies and hospital systems today and provides a behind-the-scenes look at building an innovative SaaS business in such a highly regulated space.

Whether you’re curious about the future of drug development, the role of generative AI in healthcare, or what it really takes to build a company that is changing the status quo, this episode is packed with personal stories, expert opinions, and actionable takeaways. Plus, you’ll learn why Scott’s not likely to talk cricket—despite his Aussie roots.

Tune in for an episode that’s both thought-provoking and genuinely inspiring!

Timestamps:

00:00 "Legacy of Freedom and Surprise"

05:19 Trailblazing Career and Educational Impact

06:44 Cardiac Electrophysiology Journey

13:12 "Complexity's Role in Trial Failure"

14:09 Streamlining Vaccine Design with Data

20:07 Accelerating Genome Editing Processes

22:10 Trial Data Preventing Pediatric Failures

25:28 Innovative Trial Design Insights

28:16 Outdated Clinical Trials Persist

32:53 US vs Europe: Payment & Regulation

38:14 Streamlining Drug Development Timelines

41:02 Startup's Rapid Growth Journey

43:42 Nuances in Medical Writing Explained

45:59 Documentation Workflow Experience

50:14 Insights on Clinical Trials and Investing

The Uprising Show Website: https://theuprisingshow.com/

Vivek Nanda's LinkedIn: https://www.linkedin.com/in/viveknanda1/

Vivek Nanda's Twitter: https://x.com/vickks

TopHealth Media Website: https://tophealth.care/

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In this enlightening episode of The Uprising Show, host Vivek welcomes Dr. Eve Cunningham, the new Chief Medical Officer of Cadence. Join us as we dive into Dr. Cunningham's fascinating career journey from an OBGYN physician to a tech leader in healthcare innovation.

She shares her insights on the transformation of care delivery systems, embracing technology, and her exciting new role at Cadence—an innovative force scaling remote patient care. As they delve into the future of healthcare, Dr. Cunningham offers her perspective on the impact of AI and the importance of remote care as a standard practice.

Tune in to learn about the challenges and triumphs in healthcare innovation and what the future holds for this industry. Plus, hear a fun tidbit from Dr. Cunningham's past that you won't want to miss!

Timestamps:

00:00 Career Transition to Cadence Leadership

05:52 Doctors as Entrepreneurs

09:13 "Entrepreneurial Spirit in Medicine"

11:46 Pioneering Virtual Medical Education

14:25 Tech Decisions Without Clinician Input

17:28 Strategic Healthcare Integration Insights

22:40 Costly Chronic Disease Mismanagement

23:50 Remote Care for Elderly Management

30:18 Securing Sponsorship for Clinical Integration

31:27 Remote Care Delivery with Feedback

36:39 Executive Stakeholders in Health Systems

40:26 Building Digital Health Infrastructure

44:24 Cadence's Impact on Healthcare Costs

45:39 Reducing Healthcare Costs and Admissions

50:02 Encouraging Clinical Experimentation

53:21 Early Lisa Frank Model Mystery

55:21 Unique Market Positioning

Dr. Eve Cunningham - LinkedIn - https://www.linkedin.com/in/evecunninghammd/

Cadence - https://www.cadence.care/

The Uprising Show Website: https://theuprisingshow.com/

Vivek Nanda's LinkedIn: https://www.linkedin.com/in/viveknanda1/

Vivek Nanda's Twitter: https://x.com/vickks

TopHealth Media Website: https://tophealth.care/

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In this episode of The Uprising Show, host Vivek sits down with Neal Shah, a game-changing visionary in the healthcare world. Neal is the co-founder and CEO of CareYaya Health Technologies and Counterforce Health, two groundbreaking startups making significant headway in age tech and AI for denied health insurance claims. With a profound personal journey shaping his ventures, Neal Shah shares his insights on redefining caregiving through tech innovation and addressing the critical issues in the elder care system and insurance claims. Neal's life's work is driven by both personal caregiving experiences and a deep desire to make a social impact.

Tune in to learn how Neal is innovating the healthcare landscape by bringing together young, tech-savvy caregivers with those in need and leveraging AI to empower patients in fighting insurance claim denials. Beyond his professional endeavors, Neal shares fascinating insights from his passion for reading, drawing connections between distant fields and historical patterns.

Whether you're interested in healthcare innovation or looking for inspiration from someone reshaping an industry based on personal challenges, this episode is packed with enlightening perspectives and actionable insights.

Timestamps:

00:00 Youngest Partner Turnaround Success

05:32 From Finance to Caregiving Mission

08:46 Impending Crisis in Care Industry

10:52 "Uberizing Elder Care Industry"

15:11 Streamlining Gray Market into Online Care

20:06 "Care for America: Experiential Education"

20:52 Healthcare Experience Program Benefits

26:32 Medical Billing and Necessity Issues

29:36 Agentic AI for Stress-Free Tasks

33:01 Lean Appeal Costs Barrier

34:45 Healthcare Market Perspective Needed

37:23 Negotiating Care Costs with NPS

42:22 Galactic Cycles and Human Intelligence

45:36 "Excitement for Caregiving Tech"

Neal Shah - https://www.linkedin.com/in/neal-shah-careyaya/

CareYaya - https://www.careyaya.org/

Counterforce Health - https://www.counterforcehealth.org/

The Uprising Show Website: https://theuprisingshow.com/

Vivek Nanda's LinkedIn: https://www.linkedin.com/in/viveknanda1/

Vivek Nanda's Twitter: https://x.com/vickks

TopHealth Media Website: https://tophealth.care/

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In this episode of The Uprising Show, host Vivek chats with Dr. Carmen Messerlian, a pioneering reproductive epidemiologist, about her journey and groundbreaking work in fertility health. Dr. Carmen Messerlian is the founder of Vie Science. Discover how her personal history and innovative company, Vie Science, aim to revolutionize reproductive health.

• Dr. Carmen Messerlian's immigrant upbringing and how it influenced her career.
• The concept of generational health and its impact on fertility.
• The inception and mission of Vie Science in reimagining fertility care.
• How environmental factors and personal health play a critical role in reproductive success.
• The future of fertility and longevity health through preventative measures and AI-powered solutions.

Timestamps:

00:00 "Childhood in a Family Business"

04:24 Immigrant Family Sacrifices and Struggles

09:43 Generational Trauma and Health Impact

11:44 Legacy Beyond Money and Status

16:35 Mapping the Human Exposome

19:51 Parental Environment's Impact on Offspring

21:21 "Mapping Life's Legacy Continuum"

24:43 AI-Driven Precision Medicine Models

28:31 Vie Company: Fertility and Health Innovations

31:46 Fertility's Impact on Longevity

35:52 Minimizing Endocrine Disruptor Exposure

40:37 Enhancing Fertility through Protein Editing

43:48 Personalized AI for Fertility Success

46:17 "Exploring Consciousness Beyond Reality"

48:00 Infinite Potential: Inner and Outer Worlds

Vie Science Website - https://vie.science/

Dr. Carmen Messerlian LinkedIn - https://www.linkedin.com/in/drmesserlian/

The Uprising Show Website: https://theuprisingshow.com/

Vivek Nanda's LinkedIn: https://www.linkedin.com/in/viveknanda1/

Vivek Nanda's Twitter: https://x.com/vickks

TopHealth Media Website: https://tophealth.care/

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Welcome to The Uprising Show, where today, we're diving deep into the world of biotech and AI with a truly inspiring guest, Dr. Pranam Chatterjee. At just 32 years old, Pranam has already accomplished an impressive array of achievements. He's a professor at Duke University, a co-founder of multiple biotech companies, and a trailblazer in the fields of genetic engineering and AI-driven biology.

In this episode, we'll explore Pranam's fascinating journey from a small town in Georgia, where he grew up in a family of scientists, to becoming a pioneer at the forefront of biotech innovation. Pranam will share how his early interest in religion transitioned into a passion for science and AI, leading him to groundbreaking advancements in genome and proteome editing.

We'll also hear about his exciting work with companies like Gameto and UbiquiTx, aiming to revolutionize fertility treatments and cancer therapeutics. Plus, Pranam opens up about the ethical implications of gene editing and the incredible potential of AI in solving some of the world's biggest challenges. Tune in to discover how Pranam Chatterjee is changing the future of biotechnology and what drives his relentless pursuit of knowledge and innovation.

Timestamps:

00:00 Generative AI in Biotech Innovations

06:10 AI Transforming Biotechnology Journey

09:31 "Modern Media Company Evolution"

10:43 AI Innovations in Biotechnology

14:10 Advancements in CRISPR Gene Editing

17:24 Targeting Disease-Causing Proteins

20:41 Targeted Cancer Therapy Innovation

25:17 Stem Cells and Regenerative Medicine

28:44 Breakthrough in Stem-to-Ovarian Cell Conversion

32:02 Reproductive System Trial Success?

35:26 Founder Supporting Scientific Ventures

37:19 "Academic Innovation to Startups"

41:20 Gene Editing: Easy But Risky

44:47 AI-Driven Antiviral Drug Development

47:32 Popular Music Transformed for String Quartet

50:26 Embracing Vulnerability for Growth

Pranam Chatterjee - LinkedIn - https://www.linkedin.com/in/pranamanam/

Gameto - https://www.gametogen.com/

UbiquiTx - https://www.ubiquitx.com/

The Uprising Show Website: https://theuprisingshow.com/

Vivek Nanda's LinkedIn: https://www.linkedin.com/in/viveknanda1/

Vivek Nanda's Twitter: https://x.com/vickks

TopHealth Media Website: https://tophealth.care/

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Explore the intersection of technology and healthcare with Dr. Joe Morgan and host Vivek on The Uprising Show. Delve into how XR and AI are reshaping patient care, innovation, and the future of the healthcare industry.

• Discover Dr. Joe Morgan's journey from anesthesiologist to tech entrepreneur with Waya Health.
• Learn about the motivations and insights leading to the creation of Waya Health.
• Understand the challenges and triumphs of introducing XR technology into healthcare.
• Examine the current state of XR technology and its applications within the healthcare industry.
• Gain insights into the long-term vision for Waya Health and the future of healthcare innovation.

Timestamps:

00:00 From Biology to Finance Spiral

04:45 Economic Backgrounds and Risk Tolerance

08:11 Journey into Healthcare Innovation

13:10 Extended Reality's Role in Healthcare

14:37 "Surgery-Induced Opioid Dependency"

20:10 Enterprise Value in Extended Reality

22:16 Metaverse and Reality Hype Clash

25:19 "AI and XR Future Integration"

28:33 Optimistic Outlook on Enterprise Tech

31:53 "Hardware Focus: Consumer vs. Enterprise"

36:46 Commitment Drives Healthcare Tech Success

40:10 Predictable Six-Month Healthcare Solution

42:54 Building Experiences for Patient Care

46:10 Pros and Cons of Innovation

49:49 "Convergent Health: Data to Action"

3 fun facts that were revealed in this recording:

1. Dr. Joe Morgan is very good at playing "Name That Tune" and can recognize songs within a couple of bars, although he admits he can't sing.

2. As a child, Dr. Morgan built and sold computers for money, showcasing his early interest in technology long before venturing into healthcare innovation.

3. Dr. Morgan had an adventurous period after leaving a finance job where he traveled across the country and lived out of his car for three to four months, visiting friends and national parks.

Dr. Joe Morgan's LinkedIn - https://www.linkedin.com/in/jmorganwellovate/

Waya Health - http://www.wayahealth.com

The Uprising Show Website: https://theuprisingshow.com/

Vivek Nanda's LinkedIn: https://www.linkedin.com/in/viveknanda1/

Vivek Nanda's Twitter: https://x.com/vickks

TopHealth Media Website: https://tophealth.care/

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Join Vivek as he chats with Seth Turnoff, a man of many talents and experiences. Dive into Seth's journey from a touring drummer to a healthcare marketing innovator, uncovering unique insights along the way.

• Seth Turnoff shares his unconventional career path and entrepreneurial spirit.
• Explore the intricacies of patient acquisition in healthcare.
• Learn about hyper-targeted marketing and its impact on healthcare practices.
• Discover Seth’s take on the power of personal branding, including his signature mustache.
• Gain insights into effective strategies and common pitfalls in healthcare marketing.

Timestamps:

00:00 Entrepreneurial Pivoting and Client Needs

04:41 Seeking Purpose Beyond Work

09:14 Navigating Complex Team Dynamics

12:07 Healthcare Marketing Challenges & Opportunities

14:32 Targeted Marketing for Success

18:39 Opt-In Consumer Data Advertising

20:34 "Connecting Healthcare Marketing to Revenue"

24:37 Unexpected Mustache Journey

27:48 Smallest Mustache in Wild Room

31:12 Understanding Patient Care Journey

34:58 Targeted Medical Campaign Strategy

37:11 Referral Network Success Strategy

39:30 Iterative Experimentation in Practices

42:43 Innovative Cold Email Strategies

45:49 "Accountability and Resolution Strategy"

50:11 "Insightful Journey and Mustache Secrets"

Seth Turnoff's LinkedIn - https://www.linkedin.com/in/sethturnoff/

Seth's Company - https://custommedicalmarketing.com/

The Uprising Show Website: https://theuprisingshow.com/

Vivek Nanda's LinkedIn: https://www.linkedin.com/in/viveknanda1/

Vivek Nanda's Twitter: https://x.com/vickks

TopHealth Media Website: https://tophealth.care/